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GLP-1 receptor activation inhibits VLDL production and reverses hepatic steatosis by decreasing hepatic lipogenesis in high-fat-fed APOE∗ 3-Leiden mice

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The anti-inflammatory effect can also be partially attributed to the direct antioxidant action of polyphenols (reducing NF-κB activation), but GPCR signaling is a key upstream regulator of inflammation that cinnamon influences